Multicenter dose-escalation Phase I trial of mitomycin C pressurized intraperitoneal aerosolized chemotherapy in combination with systemic chemotherapy for appendiceal and colorectal peritoneal metastases: rationale and design

Peritoneal metastasis (PM) from appendiceal cancer or colorectal cancer (CRC) has significant morbidity and limited survival. Pressurized intraperitoneal aerosolized chemotherapy (PIPAC) is a minimally invasive approach to treat PM. We aim to conduct a dose-escalation trial of mitomycin C (MMC)-PIPA...

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Bibliographic Details
Main Authors: Raoof Mustafa, Sullivan Kevin M., Frankel Paul H., Fakih Marwan, Synold Timothy W., Lim Dean, Woo Yanghee, Paz Isaac Benjamin, Fong Yuman, Thomas Rebecca Meera, Chang Sue, Eng Melissa, Tinsley Raechelle, Whelan Richard L., Deperalta Danielle, Reymond Marc A., Jones Jeremy, Merchea Amit, Dellinger Thanh H.
Format: Article
Language:English
Published: De Gruyter 2022-06-01
Series:Pleura and Peritoneum
Subjects:
Online Access:https://doi.org/10.1515/pp-2022-0116