Cost-effectiveness and cost–utility analysis of the use of clopidogrel and pantoprazole in comparison with clopidogrel and omeprazole for the secondary prevention of myocardial infarction in Iran
Objective: Gastrointestinal bleeding, a side effect of clopidogrel, is usually prevented by proton-pump inhibitors (PPIs). Due to omeprazole's inhibitory effects on the liver enzyme CYP2C19, its concomitant use with clopidogrel is argued to increase the risk of myocardial infarction (MI) recurr...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
Wolters Kluwer Medknow Publications
2021-01-01
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Series: | Journal of Research in Pharmacy Practice |
Subjects: | |
Online Access: | http://www.jrpp.net/article.asp?issn=2319-9644;year=2021;volume=10;issue=2;spage=90;epage=95;aulast= |