Cost-effectiveness and cost–utility analysis of the use of clopidogrel and pantoprazole in comparison with clopidogrel and omeprazole for the secondary prevention of myocardial infarction in Iran

Objective: Gastrointestinal bleeding, a side effect of clopidogrel, is usually prevented by proton-pump inhibitors (PPIs). Due to omeprazole's inhibitory effects on the liver enzyme CYP2C19, its concomitant use with clopidogrel is argued to increase the risk of myocardial infarction (MI) recurr...

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Bibliographic Details
Main Authors: Mohammadreza Amirsadri, Valiollah Hajhashemi, Amir Shahriar Asemi
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2021-01-01
Series:Journal of Research in Pharmacy Practice
Subjects:
Online Access:http://www.jrpp.net/article.asp?issn=2319-9644;year=2021;volume=10;issue=2;spage=90;epage=95;aulast=