Effects of dietary eicosapentaenoic acid (EPA) supplementation in high-fat fed mice on lipid metabolism and apelin/APJ system in skeletal muscle.

Effects of dietary eicosapentaenoic acid (EPA) supplementation in high-fat fed mice on lipid metabolism and apelin/APJ system in skeletal muscle.

Various studies have shown that eicosapentaenoic acid (EPA) has beneficial effects on obesity and associated disorders. Apelin, the ligand of APJ receptor also exerts insulin-sensitizing effects especially by improving muscle metabolism. EPA has been shown to increase apelin production in adipose ti...

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Bibliographic Details
Main Authors: Chantal Bertrand, Angelica Pignalosa, Estelle Wanecq, Chloé Rancoule, Aurélie Batut, Simon Deleruyelle, Lillà Lionetti, Philippe Valet, Isabelle Castan-Laurell
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3820669?pdf=render

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http://europepmc.org/articles/PMC3820669?pdf=render

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