Host signaling and EGR1 transcriptional control of human cytomegalovirus replication and latency.

Host signaling and EGR1 transcriptional control of human cytomegalovirus replication and latency.

Sustained phosphotinositide3-kinase (PI3K) signaling is critical to the maintenance of alpha and beta herpesvirus latency. We have previously shown that the beta-herpesvirus, human cytomegalovirus (CMV), regulates epidermal growth factor receptor (EGFR), upstream of PI3K, to control states of latenc...

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Bibliographic Details
Main Authors: Jason Buehler, Ethan Carpenter, Sebastian Zeltzer, Suzu Igarashi, Michael Rak, Iliyana Mikell, Jay A Nelson, Felicia Goodrum
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-11-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1008037

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https://doi.org/10.1371/journal.ppat.1008037

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