Deoxycholic Acid, a Secondary Bile Acid, Increases Cardiac Output and Blood Pressure in Rats

Deoxycholic Acid, a Secondary Bile Acid, Increases Cardiac Output and Blood Pressure in Rats

Background: Deoxycholic acid (DCA) is a secondary bile acid produced by gut bacteria. Elevated serum concentrations of DCA are observed in cardiovascular disease (CVD). We hypothesized that DCA might influence hemodynamic parameters in rats. Methods: The concentration of DCA in systemic blood was me...

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Bibliographic Details
Main Authors: Artur Nowiński, Dawid Chabowski, Joanna Giebułtowicz, Marta Aleksandrowicz, Marcin Ufnal
Format: Article
Language:English
Published: MDPI AG 2023-12-01
Series:Nutrients
Subjects:
deoxycholic acid
blood pressure
cardiac output
vasodilatation
bacterial metabolites
Online Access:https://www.mdpi.com/2072-6643/16/1/32

Internet

https://www.mdpi.com/2072-6643/16/1/32

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