Exploring the Control of PARP1 Levels in High-Grade Serous Ovarian Cancer

High-grade serous ovarian cancer (HGSOC) is a leading cause of mortality from gynecologic malignancies worldwide. Although a transformative improvement has been shown with the introduction of PARP (poly(ADP-ribose) polymerase) inhibitors, the emergence of resistance to these drugs represents a thera...

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Bibliographic Details
Main Authors: Giuseppina Raspaglio, Marianna Buttarelli, Natalia Cappoli, Alessandra Ciucci, Anna Fagotti, Giovanni Scambia, Daniela Gallo
Format: Article
Language:English
Published: MDPI AG 2023-04-01
Series:Cancers
Subjects:
Online Access:https://www.mdpi.com/2072-6694/15/8/2361