Single-Cell RNA Sequencing Reveals Smooth Muscle Cells Heterogeneity in Experimental Aortic Dissection

Single-Cell RNA Sequencing Reveals Smooth Muscle Cells Heterogeneity in Experimental Aortic Dissection

Purpose: This study aims to illustrate the cellular landscape in the aorta of experimental aortic dissection (AD) and elaborate on the smooth muscle cells (SMCs) heterogeneity and functions among various cell types.Methods: Male Apolipoprotein deficient (ApoE−/−) mice at 28 weeks of age were infused...

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Bibliographic Details
Main Authors: Cheng Xu, Xiaowei Liu, Xiaoxin Fang, Lei Yu, Hui Chong Lau, Danlei Li, Xiaoman Liu, Haili Li, Justin Ren, Baohui Xu, Jianjun Jiang, Lijiang Tang, Xiaofeng Chen
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-08-01
Series:Frontiers in Genetics
Subjects:
aortic dissection
single-cell RNA sequencing
gene ontology enrichment analysis
smooth muscle cells
KEGG enrichment analysis
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2022.836593/full

Internet

https://www.frontiersin.org/articles/10.3389/fgene.2022.836593/full

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