Virtual Screening and Molecular Dynamics Simulation Study of Influenza Polymerase PB2 Inhibitors

Virtual Screening and Molecular Dynamics Simulation Study of Influenza Polymerase PB2 Inhibitors

Influenza A virus is the main cause of worldwide epidemics and annual influenza outbreaks in humans. In this study, a virtual screen was performed to identify compounds that interact with the PB2 cap-binding domain (CBD) of influenza A polymerase. A virtual screening workflow based on Glide docking...

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Bibliographic Details
Main Authors: Keli Zong, Lei Xu, Yuxin Hou, Qian Zhang, Jinjing Che, Lei Zhao, Xingzhou Li
Format: Article
Language:English
Published: MDPI AG 2021-11-01
Series:Molecules
Subjects:
virtual screening
influenza virus
polymerase basic protein 2
inhibitor
molecular dynamics simulations
Online Access:https://www.mdpi.com/1420-3049/26/22/6944

Internet

https://www.mdpi.com/1420-3049/26/22/6944

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