Building synthetic sterols computationally – unlocking the secrets of evolution?

Cholesterol is vital in regulating the physical properties of animal cell membranes. While it remains unclear what renders cholesterol so unique, it is known that other sterols are less capable in modulating membrane properties, and there are membrane proteins whose function is dependent on choleste...

Full description

Bibliographic Details
Main Authors: Tomasz eRog, Sanja ePöyry, Ilpo eVattulainen
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-08-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fbioe.2015.00121/full