Rapid nanomolding of nanotopography on flexible substrates to control muscle cell growth with enhanced maturation

Abstract In vivo, multiple biophysical cues provided by highly ordered connective tissues of the extracellular matrix regulate skeletal muscle cells to align in parallel with one another. However, in routine in vitro cell culture environments, these key factors are often missing, which leads to chan...

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Bibliographic Details
Main Authors: Cong Wu, Chriss S. M. Chin, Qingyun Huang, Ho-Yin Chan, Xinge Yu, Vellaisamy A. L. Roy, Wen J. Li
Format: Article
Language:English
Published: Nature Publishing Group 2021-11-01
Series:Microsystems & Nanoengineering
Online Access:https://doi.org/10.1038/s41378-021-00316-4