Sevoflurane postconditioning alleviates hypoxia-reoxygenation injury of cardiomyocytes by promoting mitochondrial autophagy through the HIF-1/BNIP3 signaling pathway

Background Sevoflurane postconditioning (SpostC) can alleviate hypoxia-reoxygenation injury of cardiomyocytes; however, the specific mechanism remains unclear. This study aimed to investigate whether SpostC promotes mitochondrial autophagy through the hypoxia-inducible factor-1 (HIF-1)/BCL2/adenovir...

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Bibliographic Details
Main Authors: Long Yang, Jianjiang Wu, Peng Xie, Jin Yu, Xin Li, Jiang Wang, Hong Zheng
Format: Article
Language:English
Published: PeerJ Inc. 2019-06-01
Series:PeerJ
Subjects:
Online Access:https://peerj.com/articles/7165.pdf