A tormentic acid-homopiperazine-rhodamine B conjugate of single-digit nanomolar cytotoxicity and high selectivity for several human tumor cell lines
Tormentic acid and euscaphic acid were isolated from plant material and transformed into amides holding an extra rhodamine B moiety; these compounds were screened for their cytotoxic activity employing a panel of human tumor cell lines and non-malignant fibroblasts. Prerequisites for both high cytot...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2022-08-01
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| Series: | European Journal of Medicinal Chemistry Reports |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2772417422000152 |