Role of the Circadian Gas-Responsive Hemeprotein NPAS2 in Physiology and Pathology

Role of the Circadian Gas-Responsive Hemeprotein NPAS2 in Physiology and Pathology

Neuronal PAS domain protein 2 (NPAS2) is a hemeprotein comprising a basic helix–loop–helix domain (bHLH) and two heme-binding sites, the PAS-A and PAS-B domains. This protein acts as a pyridine nucleotide-dependent and gas-responsive CO-dependent transcription factor and is encoded by a gene whose e...

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Bibliographic Details
Main Authors: Emanuele Murgo, Tommaso Colangelo, Maria Marina Bellet, Francesco Malatesta, Gianluigi Mazzoccoli
Format: Article
Language:English
Published: MDPI AG 2023-10-01
Series:Biology
Subjects:
NPAS2
circadian
rhythmicity
molecular clockwork
PAS domain
heme
Online Access:https://www.mdpi.com/2079-7737/12/10/1354

Internet

https://www.mdpi.com/2079-7737/12/10/1354

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