Defining the Homo- and Heterodimerization Propensities of Metabotropic Glutamate Receptors

Defining the Homo- and Heterodimerization Propensities of Metabotropic Glutamate Receptors

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Summary: The eight metabotropic glutamate receptors (mGluRs) serve critical modulatory roles throughout the nervous system. The molecular diversity of mGluRs is thought to be further expanded by the formation of heterodimers, but the co-expression of mGluR subtypes at the cellular level and the rela...

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Bibliographic Details
Main Authors: Joon Lee, Hermany Munguba, Vanessa A. Gutzeit, Melanie Kristt, Jeremy S. Dittman, Joshua Levitz
Format: Article
Language:English
Published: Elsevier 2020-05-01
Series:Cell Reports
Subjects:
Metabotropic Glutamate Receptor
G Protein-Coupled Receptor
Neuromodulation
Heterodimerization
Single cell RNA sequencing
single molecule fluorescence
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124720305544

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http://www.sciencedirect.com/science/article/pii/S2211124720305544

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