Spike-based adenovirus vectored COVID-19 vaccine does not aggravate heart damage after ischemic injury in mice

Spike-based adenovirus vectored COVID-19 vaccine does not aggravate heart damage after ischemic injury in mice

The safety of spike-based adenovirus type-5 vectored COVID-19 vaccine is evaluated, showing it neither affects the survival and function of human cardiac cells and engineered heart tissues nor aggravates heart damage in mice after ischemic injury.

Bibliographic Details
Main Authors: Shanshan Gu, Zhongyan Chen, Xiangfu Meng, Ge Liu, He Xu, Liying Huang, Linwei Wu, Jixing Gong, Ding Chen, Bingqing Xue, Lihang Zhu, Zhongjun Wan, Jianqing Lin, Xiaolong Cai, Xiaoyan Zhang, Jia Wang, Donghui Zhang, Nan Cao
Format: Article
Language:English
Published: Nature Portfolio 2022-09-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-022-03875-y

Internet

https://doi.org/10.1038/s42003-022-03875-y

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