Sustained adenosine exposure causes endothelial mitochondrial dysfunction via equilibrative nucleoside transporters
Adenosine is a potent signaling molecule that has paradoxical effects on lung diseases. We have previously demonstrated that sustained adenosine exposure by inhibition of adenosine degradation impairs lung endothelial barrier integrity and causes intrinsic apoptosis through equilibrative nucleoside...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
Wiley
2020-05-01
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Series: | Pulmonary Circulation |
Online Access: | https://doi.org/10.1177/2045894020924994 |