Conformational sampling of CMT-2D associated GlyRS mutations
During protein synthesis, aminoacyl-tRNA synthetases covalently link amino acids with their cognate tRNAs. Amino acid mutations in glycyl-tRNA synthetase can disrupt protein synthesis and lead to a neurological disorder known as Charcot-Marie-Tooth disease type 2D (CMT-2D). Several studies employing...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2022-01-01
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| Series: | Brain Multiphysics |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2666522022000119 |