The biological role and immunotherapy of gangliosides and GD3 synthase in cancers

Gangliosides are a large subfamily of glycosphingolipids that broadly exist in the nervous system and interact with signaling molecules in the lipid rafts. GD3 and GD2 are two types of disialogangliosides (GDs) that include two sialic acid residues. The expression of GD3 and GD2 in various cancers i...

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Bibliographic Details
Main Authors: Shangqi Cao, Xu Hu, Shangqing Ren, Yaohui Wang, Yanxiang Shao, Kan Wu, Zhen Yang, Weixiao Yang, Gu He, Xiang Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-02-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2023.1076862/full