Simian Varicella Virus Infects Enteric Neurons and α4β7 Integrin-Expressing Gut-Tropic T-Cells in Nonhuman Primates

Simian Varicella Virus Infects Enteric Neurons and α4β7 Integrin-Expressing Gut-Tropic T-Cells in Nonhuman Primates

The pathogenesis of enteric zoster, a rare debilitating complication of reactivation of latent varicella-zoster virus (VZV) in the enteric nervous system (ENS), is largely unknown. Infection of monkeys with the closely related Varicellovirus simian varicella virus (SVV) mimics VZV disease in humans....

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Bibliographic Details
Main Authors: Werner J. D. Ouwendijk, Suzanne van Veen, Tamana Mehraban, Ravi Mahalingam, Georges M. G. M. Verjans
Format: Article
Language:English
Published: MDPI AG 2018-03-01
Series:Viruses
Subjects:
varicella-zoster virus
simian varicella virus
enteric nervous system
nonhuman primate
T-cells
Online Access:http://www.mdpi.com/1999-4915/10/4/156

Internet

http://www.mdpi.com/1999-4915/10/4/156

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