In vitro antileishmanial activity and molecular docking studies of lupeol and monostearin, isolated from Parkia biglobosa

In vitro antileishmanial activity and molecular docking studies of lupeol and monostearin, isolated from Parkia biglobosa

Parkia biglobosa (Leguminosae) is used traditionally for managing leishmaniasis. However, there are no reports of the antileishmanial constituents from the plant. This study is aimed at isolating antileishmanial compounds, from the stem bark of P. biglobosa, and assessing their mechanism of action u...

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Bibliographic Details
Main Authors: Thomas Osafo, Trudy Janice Philips, Abigail Kusiwaa Adomako, Lawrence Sheringham Borquaye, Edmund Ekuadzi, Regina Appiah-Opong, Rita Akosua Dickson
Format: Article
Language:English
Published: Elsevier 2023-03-01
Series:Scientific African
Subjects:
Triterpenes
Monoglycerides
Parkia clappertoniana
Leishmaniasis
Docking
Trypanothione reductase
Online Access:http://www.sciencedirect.com/science/article/pii/S2468227622003696

Internet

http://www.sciencedirect.com/science/article/pii/S2468227622003696

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