Characterization of SALL2 Gene Isoforms and Targets Across Cell Types Reveals Highly Conserved Networks

Characterization of SALL2 Gene Isoforms and Targets Across Cell Types Reveals Highly Conserved Networks

The SALL2 transcription factor, an evolutionarily conserved gene through vertebrates, is involved in normal development and neuronal differentiation. In disease, SALL2 is associated with eye, kidney, and brain disorders, but mainly is related to cancer. Some studies support a tumor suppressor role a...

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Bibliographic Details
Main Authors: Carlos Farkas, Aracelly Quiroz, Claudia Alvarez, Viviana Hermosilla, Carlos F. Aylwin, Alejandro Lomniczi, Ariel F. Castro, Matias I. Hepp, Roxana Pincheira
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-02-01
Series:Frontiers in Genetics
Subjects:
SALL2
isoforms
transcription factor network
PODXL
ENCODE ChIP-seq
Glioblastoma
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2021.613808/full

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https://www.frontiersin.org/articles/10.3389/fgene.2021.613808/full

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