Natural killer cells for immunotherapy – Advantages of cell lines over blood NK cells

Natural killer cells are potent cytotoxic effector cells for cancer therapy and potentially for severe viral infections. However, there are technical challenges to obtain sufficient numbers of functionally active NK cells form a patient’s blood since they represent only 10% of the lymphocytes. Espec...

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Bibliographic Details
Main Authors: Hans eKlingemann, Laurent eBoissel, Frances eToneguzzo
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-03-01
Series:Frontiers in Immunology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2016.00091/full