Cerebral topography of vesicular cholinergic transporter changes in neurologically intact adults: A [18F]FEOBV PET study

Acetylcholine plays a major role in brain cognitive and motor functions with regional cholinergic terminal loss common in several neurodegenerative disorders. We describe age-related declines of regional cholinergic neuron terminal density in vivo using the positron emission tomography (PET) ligand...

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Bibliographic Details
Main Authors: Prabesh Kanel, Sygrid van der Zee, Carlos A. Sanchez-Catasus, Robert A. Koeppe, Peter J.H. Scott, Teus van Laar, Roger L. Albin, Nicolaas I. Bohnen
Format: Article
Language:English
Published: Elsevier 2022-01-01
Series:Aging Brain
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2589958922000111