Cerebral topography of vesicular cholinergic transporter changes in neurologically intact adults: A [18F]FEOBV PET study
Acetylcholine plays a major role in brain cognitive and motor functions with regional cholinergic terminal loss common in several neurodegenerative disorders. We describe age-related declines of regional cholinergic neuron terminal density in vivo using the positron emission tomography (PET) ligand...
Main Authors: | Prabesh Kanel, Sygrid van der Zee, Carlos A. Sanchez-Catasus, Robert A. Koeppe, Peter J.H. Scott, Teus van Laar, Roger L. Albin, Nicolaas I. Bohnen |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2022-01-01
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Series: | Aging Brain |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2589958922000111 |
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