RSAD2 is abundant in atherosclerotic plaques and promotes interferon-induced CXCR3-chemokines in human smooth muscle cells

RSAD2 is abundant in atherosclerotic plaques and promotes interferon-induced CXCR3-chemokines in human smooth muscle cells

Abstract In atherosclerotic lesions, monocyte-derived macrophages are major source of interferon gamma (IFN-γ), a pleotropic cytokine known to regulate the expression of numerous genes, including the antiviral gene RSAD2. While RSAD2 was reported to be expressed in endothelial cells of human carotid...

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Bibliographic Details
Main Authors: Assim Hayderi, Ashok K. Kumawat, Vladimir S. Shavva, Mats Dreifaldt, Birgitta Sigvant, Marcelo H. Petri, Björn Kragsterman, Peder S. Olofsson, Allan Sirsjö, Liza U. Ljungberg
Format: Article
Language:English
Published: Nature Portfolio 2024-04-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-024-58592-9

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https://doi.org/10.1038/s41598-024-58592-9

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