Circular RNAs in the human brain are tailored to neuron identity and neuropsychiatric disease

Abstract Little is known about circular RNAs (circRNAs) in specific brain cells and human neuropsychiatric disease. Here, we systematically identify over 11,039 circRNAs expressed in vulnerable dopamine and pyramidal neurons laser-captured from 190 human brains and non-neuronal cells using ultra-dee...

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Bibliographic Details
Main Authors: Xianjun Dong, Yunfei Bai, Zhixiang Liao, David Gritsch, Xiaoli Liu, Tao Wang, Rebeca Borges-Monroy, Alyssa Ehrlich, Geidy E. Serrano, Mel B. Feany, Thomas G. Beach, Clemens R. Scherzer
Format: Article
Language:English
Published: Nature Portfolio 2023-09-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-023-40348-0