Oxidative damage of U937 human leukemic cells caused by hydroxyl radical results in singlet oxygen formation.

The exposure of human cells to oxidative stress leads to the oxidation of biomolecules such as lipids, proteins and nuclei acids. In this study, the oxidation of lipids, proteins and DNA was studied after the addition of hydrogen peroxide and Fenton reagent to cell suspension containing human leukem...

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Bibliographic Details
Main Authors: Marek Rác, Michal Křupka, Svatopluk Binder, Michaela Sedlářová, Zuzana Matušková, Milan Raška, Pavel Pospíšil
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0116958