The Adenylate Cyclase (CyaA) Toxin from <i>Bordetella pertussis</i> Has No Detectable Phospholipase A (PLA) Activity In Vitro

The Adenylate Cyclase (CyaA) Toxin from <i>Bordetella pertussis</i> Has No Detectable Phospholipase A (PLA) Activity In Vitro

The adenylate cyclase (CyaA) toxin produced in <i>Bordetella pertussis</i> is the causative agent of whooping cough. CyaA exhibits the remarkable capacity to translocate its N-terminal adenyl cyclase domain (ACD) directly across the plasma membrane into the cytosol of eukaryotic cells. O...

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Bibliographic Details
Main Authors: Alexis Voegele, Mirko Sadi, Dorothée Raoux-Barbot, Thibaut Douché, Mariette Matondo, Daniel Ladant, Alexandre Chenal
Format: Article
Language:English
Published: MDPI AG 2019-02-01
Series:Toxins
Subjects:
adenylate cyclase toxin
CyaA toxin
bordetella pertussis
phospholipase A
fluorescence
Online Access:https://www.mdpi.com/2072-6651/11/2/111

Internet

https://www.mdpi.com/2072-6651/11/2/111

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