Cadmium perturbed lipid profile and induced liver dysfunction in mice through phosphatidylcholine remodeling and promoting arachidonic acid synthesis and metabolism

Cadmium ion (Cd2+) exposure has been reported to associate with the prevalence of dyslipidemia, and contribute to the initiation and progression of nonalcoholic fatty liver disease (NAFLD). However, Cd2+ exposure perturbed specific metabolic pathways and underlying mechanisms are still unclear. In t...

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Bibliographic Details
Main Authors: Jie Gu, Anqi Kong, Chuanzhi Guo, Junlin Liu, Kongdong Li, Zhen Ren, Yang Zhou, Min Tang, Haifeng Shi
Format: Article
Language:English
Published: Elsevier 2022-12-01
Series:Ecotoxicology and Environmental Safety
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0147651322010946