Cadmium perturbed lipid profile and induced liver dysfunction in mice through phosphatidylcholine remodeling and promoting arachidonic acid synthesis and metabolism

Cadmium perturbed lipid profile and induced liver dysfunction in mice through phosphatidylcholine remodeling and promoting arachidonic acid synthesis and metabolism

Cadmium ion (Cd2+) exposure has been reported to associate with the prevalence of dyslipidemia, and contribute to the initiation and progression of nonalcoholic fatty liver disease (NAFLD). However, Cd2+ exposure perturbed specific metabolic pathways and underlying mechanisms are still unclear. In t...

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Bibliographic Details
Main Authors: Jie Gu, Anqi Kong, Chuanzhi Guo, Junlin Liu, Kongdong Li, Zhen Ren, Yang Zhou, Min Tang, Haifeng Shi
Format: Article
Language:English
Published: Elsevier 2022-12-01
Series:Ecotoxicology and Environmental Safety
Subjects:
Lipidomics
Cadmium
Fatty acid desaturase 1
Phosphatidylcholine
Arachidonic acid
Online Access:http://www.sciencedirect.com/science/article/pii/S0147651322010946

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