A systematic review of diagnostic, prognostic, and risk blood and urine biomarkers of transplant-associated thrombotic microangiopathy

A systematic review of diagnostic, prognostic, and risk blood and urine biomarkers of transplant-associated thrombotic microangiopathy

Transplant-associated thrombotic microangiopathy (TA-TMA) is an increasingly recognized complication of allogeneic and autologous hematopoietic cellular therapy (HCT), associated with significant morbidity and mortality. Although the central drivers of the disease are thought to be endothelial damag...

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Bibliographic Details
Main Authors: Michelle L. Schoettler, Harshil Bhatt, Sumithira Vasu
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-02-01
Series:Frontiers in Immunology
Subjects:
transplant associated thrombotic microangiopathy
biomarkers
complement activation
endothelial activation
sC5b-9 (serum complement membrane attack complex)
NETs (neutrophil extracellular traps)
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.1064203/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2022.1064203/full

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