Cost effective and reliable cell based ELISA as an alternative method of flow cytometry for assessment of binding activity of Vedolizumab

Cost effective and reliable cell based ELISA as an alternative method of flow cytometry for assessment of binding activity of Vedolizumab

Vedolizumab is a humanized monoclonal antibody used for inflammatory bowel disease treatment. Vedolizumab binds to the α4β7 integrin complex and inhibits its binding to mucosal addressin cell adhesion molecule-1 (MAdCAM-1). To evaluate the binding efficacy and quality control check of Vedolizumab, f...

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Bibliographic Details
Main Authors: Swati Shalini, Anu Sharma, Nripendra Nath Mishra, Ratnesh Kumar Sharma, Harish Chander, Anupkumar R. Anvikar, Subhash Chand
Format: Article
Language:English
Published: Elsevier 2023-02-01
Series:Heliyon
Subjects:
Vedolizumab
Flow cytometry
Cell based ELISA
Potency
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844023007776

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http://www.sciencedirect.com/science/article/pii/S2405844023007776

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