I-CBP112 declines overexpression of ATP-binding cassette transporters and sensitized drug-resistant MDA-MB-231 and A549 cell lines to chemotherapy drugs

I-CBP112 declines overexpression of ATP-binding cassette transporters and sensitized drug-resistant MDA-MB-231 and A549 cell lines to chemotherapy drugs

Despite extensive efforts and ongoing progress in personalized anticancer approaches, chemotherapy remains the first line or the only treatment for some tumors that may develop resistance to chemotherapeutics in time due to inter alia overexpression of ATP-binding cassette transporters. Using clinic...

Full description

Bibliographic Details
Main Authors: Magdalena Strachowska, Karolina Gronkowska, Maciej Sobczak, Marika Grodzicka, Sylwia Michlewska, Kinga Kołacz, Tuhin Sarkar, Joanna Korszun, Maksim Ionov, Agnieszka Robaszkiewicz
Format: Article
Language:English
Published: Elsevier 2023-12-01
Series:Biomedicine & Pharmacotherapy
Subjects:
CREB-binding protein/Histone acetyltransferase p300 (CBP/EP300) bromodomain inhibitor
Multi-drug resistance (MDR)
ATP-binding cassette transporters (ABC)
Triple-negative breast cancer
Non-small cell lung cancer
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332223015962

Internet

http://www.sciencedirect.com/science/article/pii/S0753332223015962

Similar Items