Resembling the bottleneck effect in p53 core network including the dephosphorylation of ATM by Wip1: A computational study
As one of the key proteins, wild-type p53 can inhibit the tumor development and regulate the cell fate. Thus, the study on p53 and its related kinetics has important physiological significance. Previous experiments have shown that wild-type p53-transcribed phosphatase one protein Wip1 can maintain t...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2022-11-01
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| Series: | Frontiers in Physics |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fphy.2022.1017218/full |