In Vivo Targeted Metabolomic Profiling of Prostanit, a Novel Anti-PAD NO-Donating Alprostadil-Based Drug

Prostanit is a novel drug developed for the treatment of peripheral arterial diseases. It consists of a prostaglandin E<sub>1</sub> (PGE<sub>1</sub>) moiety with two nitric oxide (NO) donor fragments, which provide a combined vasodilation effect on smooth muscles and vascular...

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Bibliographic Details
Main Authors: Ksenia M. Shestakova, Natalia E. Moskaleva, Natalia V. Mesonzhnik, Alexey V. Kukharenko, Igor V. Serkov, Igor I. Lyubimov, Elena V. Fomina-Ageeva, Vladimir V. Bezuglov, Mikhail G. Akimov, Svetlana A. Appolonova
Format: Article
Language:English
Published: MDPI AG 2020-12-01
Series:Molecules
Subjects:
Online Access:https://www.mdpi.com/1420-3049/25/24/5896