Adult neurogenic deficits in HIV-1 Tg26 transgenic mice

Adult neurogenic deficits in HIV-1 Tg26 transgenic mice

Abstract Background Even in the antiretroviral treatment (ART) era, HIV-1-infected patients suffer from milder forms of HIV-1-associated neurocognitive disorders (HAND). While the viral proteins Tat and gp120 have been shown to individually inhibit the proliferation and neural differentiation of neu...

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Bibliographic Details
Main Authors: Raj Putatunda, Yonggang Zhang, Fang Li, Xiao-Feng Yang, Mary F Barbe, Wenhui Hu
Format: Article
Language:English
Published: BMC 2018-10-01
Series:Journal of Neuroinflammation
Subjects:
HIV-1
HAND
Tg26 mouse
Neurogenesis
Neural stem cells
Stemness
Online Access:http://link.springer.com/article/10.1186/s12974-018-1322-2

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http://link.springer.com/article/10.1186/s12974-018-1322-2

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