Ganetespib with Methotrexate Acts Synergistically to Impede NF-κB/p65 Signaling in Human Lung Cancer A549 Cells

Ganetespib with Methotrexate Acts Synergistically to Impede NF-κB/p65 Signaling in Human Lung Cancer A549 Cells

Among the various types of cancer, lung cancer accounts for the highest number of fatalities across the globe. A combination of different cancer chemotherapeutics is regarded as an effective strategy for clinical management of different cancers. Ganetespib (GAN) is a well-established hsp90 inhibitor...

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Bibliographic Details
Main Authors: Gehad Subaiea, Syed Mohd Danish Rizvi, Hemant Kumar Singh Yadav, Turki Al Hagbani, Marwa Helmy Abdallah, El-Sayed Khafagy, Hosahalli Veerabhadrappa Gangadharappa, Talib Hussain, Amr Selim Abu Lila
Format: Article
Language:English
Published: MDPI AG 2023-02-01
Series:Pharmaceuticals
Subjects:
anticancer
ganetespib
lung cancer
methotrexate
NF-κB/p65 signaling
NSCLC
Online Access:https://www.mdpi.com/1424-8247/16/2/230

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https://www.mdpi.com/1424-8247/16/2/230

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