Construction of multiple concentration gradients for single-cell level drug screening

Abstract Isolation and manipulation of single cells play a crucial role in drug screening. However, previously reported single-cell drug screening lacked multiple-dose concentration gradient studies, which limits their ability to predict drug performance accurately. To solve this problem, we constru...

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Bibliographic Details
Main Authors: Shaofei Shen, Fangjuan Zhang, Yali Zhang, Yi Li, Yanbing Niu, Long Pang, Jinyi Wang
Format: Article
Language:English
Published: Nature Publishing Group 2023-04-01
Series:Microsystems & Nanoengineering
Online Access:https://doi.org/10.1038/s41378-023-00516-0