Photoactivatable ribonucleosides mark base-specific RNA-binding sites

RNA-protein interactions play critical roles in post-transcriptional gene regulation. Here the authors demonstrate pRBS-ID, an updated MS/MS-based method that combines the benefits of photoactivatable ribonucleosides and the chemical cleavage of RNA.

Bibliographic Details
Main Authors: Jong Woo Bae, Sangtae Kim, V. Narry Kim, Jong-Seo Kim
Format: Article
Language:English
Published: Nature Portfolio 2021-10-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-021-26317-5