Loss of CLCA4 promotes epithelial-to-mesenchymal transition in breast cancer cells.

The epithelial to mesenchymal transition (EMT) is a developmental program in which epithelial cells downregulate their cell-cell junctions, acquire spindle cell morphology and exhibit cellular motility. In breast cancer, EMT facilitates invasion of surrounding tissues and correlates closely with can...

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Bibliographic Details
Main Authors: Yang Yu, Vijay Walia, Randolph C Elble
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3873418?pdf=render