Loss of CLCA4 promotes epithelial-to-mesenchymal transition in breast cancer cells.
The epithelial to mesenchymal transition (EMT) is a developmental program in which epithelial cells downregulate their cell-cell junctions, acquire spindle cell morphology and exhibit cellular motility. In breast cancer, EMT facilitates invasion of surrounding tissues and correlates closely with can...
Main Authors: | Yang Yu, Vijay Walia, Randolph C Elble |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2013-01-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC3873418?pdf=render |
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