Thrombospondin-1 Plays an Essential Role in Yes-Associated Protein Nuclear Translocation during the Early Phase of <i>Trypanosoma cruzi</i> Infection in Heart Endothelial Cells

Thrombospondin-1 Plays an Essential Role in Yes-Associated Protein Nuclear Translocation during the Early Phase of <i>Trypanosoma cruzi</i> Infection in Heart Endothelial Cells

The protozoan parasite <i>Trypanosoma cruzi</i> is the causative agent of Chagas disease. This neglected tropical disease causes severe morbidity and mortality in endemic regions. About 30% of <i>T. cruzi</i> infected individuals will present with cardiac complications. Invas...

Full description

Bibliographic Details
Main Authors: Ashutosh Arun, Kayla J. Rayford, Ayorinde Cooley, Girish Rachakonda, Fernando Villalta, Siddharth Pratap, Maria F. Lima, Nader Sheibani, Pius N. Nde
Format: Article
Language:English
Published: MDPI AG 2020-07-01
Series:International Journal of Molecular Sciences
Subjects:
Chagas heart disease
heart endothelial cells
hippo signaling
transcriptional enhancer factor (TEF) family/TEA domain (TEAD) family
<i>Trypanosoma cruzi</i>
yes-associated protein1
Online Access:https://www.mdpi.com/1422-0067/21/14/4912

Internet

https://www.mdpi.com/1422-0067/21/14/4912

Similar Items