Prophylactic exercise-derived circulating exosomal miR-125a-5p promotes endogenous revascularization after hindlimb ischemia by targeting endothelin converting enzyme 1

Prophylactic exercise-derived circulating exosomal miR-125a-5p promotes endogenous revascularization after hindlimb ischemia by targeting endothelin converting enzyme 1

BackgroundProphylactic exercise improves clinical outcomes in patients experiencing severe ischemic diseases. Previous studies have shown that exercise could alter the amount or content of circulating exosomes. However, little is known about the role of precursory exercise-derived circulating exosom...

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Bibliographic Details
Main Authors: Xueting Qiu, Jipeng Zhou, Yanying Xu, Longsheng Liao, Huijun Yang, Yuan Xiang, Zhengshi Zhou, Quan Sun, Minghong Chen, Jiaxiong Zhang, Wanzhou Wu, Lingping Zhu, Baiyang You, Lingfang He, Ying Luo, Zhenyu Li, Chuanchang Li, Yongping Bai
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-07-01
Series:Frontiers in Cardiovascular Medicine
Subjects:
exercise
miR-125a-5p
circulating
exosome
revascularization
Online Access:https://www.frontiersin.org/articles/10.3389/fcvm.2022.881526/full

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https://www.frontiersin.org/articles/10.3389/fcvm.2022.881526/full

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