Estimating genome-wide DNA methylation heterogeneity with methylation patterns

Estimating genome-wide DNA methylation heterogeneity with methylation patterns

Abstract Background In a heterogeneous population of cells, individual cells can behave differently and respond variably to the environment. This cellular diversity can be assessed by measuring DNA methylation patterns. The loci with variable methylation patterns are informative of cellular heteroge...

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Bibliographic Details
Main Authors: Pei-Yu Lin, Ya-Ting Chang, Yu-Chun Huang, Pao-Yang Chen
Format: Article
Language:English
Published: BMC 2023-11-01
Series:Epigenetics & Chromatin
Subjects:
DNA Methylation pattern
Methylation heterogeneity, DNA methylation
Mathematical modelling
Bisulfite sequencing
Enzymatic methyl sequencing
Next Generation Sequencing
Online Access:https://doi.org/10.1186/s13072-023-00521-7

Internet

https://doi.org/10.1186/s13072-023-00521-7

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