Administration of mRNA-Nanomedicine-Augmented Calvarial Defect Healing via Endochondral Ossification

Administration of mRNA-Nanomedicine-Augmented Calvarial Defect Healing via Endochondral Ossification

Large-area craniofacial defects remain a challenge for orthopaedists, hastening the need to develop a facile and safe tissue engineering strategy; osteoconductive material and a combination of optimal growth factors and microenvironment should be considered. Faced with the unmet need, we propose tha...

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Bibliographic Details
Main Authors: Hsi-Kai Tsou, Cheng-Hsin Wu, Long Yi Chan, Kazunori Kataoka, Nanae Itokazu, Minoru Tsuzuki, Hsuan Hu, Guan-Yu Zhuo, Keiji Itaka, Chin-Yu Lin
Format: Article
Language:English
Published: MDPI AG 2023-07-01
Series:Pharmaceutics
Subjects:
mRNA medicine
polyplex nanomicelle
calvarial defect
endochondral ossification
tissue engineering
Online Access:https://www.mdpi.com/1999-4923/15/7/1965

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https://www.mdpi.com/1999-4923/15/7/1965

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