ANALGESIC AND ANTI-INFLAMMATORY PROPERTIES OF THE NOVEL 3– ALKOXY -1,2-DIHYDRO-3H-1,4-BENZODIAZEPIN-2- ONES
The analgesic activity of the series of 1,2-dihydro-3H-1,4-benzodiazepin-2-ones substituted in position 3 was studied. As a leader, it was revealed the compound 8 (3-propoxy-7-bromo-5-(2’-chloro)phenyl-1,2-dihydro-3H-1,4-benzodiazepin-2-one) with ED50 value of 0,030 ± 0,007 mg/kg, which also has dem...
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Odessa I. I. Mechnikov National University
2014-11-01
|
| Series: | Vìsnik Odesʹkogo Nacìonalʹnogo Unìversitetu: Hìmìâ |
| Subjects: | |
| Online Access: | http://heraldchem.onu.edu.ua/article/view/31120 |