Genome Reshuffling for Advanced Intercross Permutation (GRAIP): simulation and permutation for advanced intercross population analysis.

Advanced intercross lines (AIL) are segregating populations created using a multi-generation breeding protocol for fine mapping complex trait loci (QTL) in mice and other organisms. Applying QTL mapping methods for intercross and backcross populations, often followed by naïve permutation of individu...

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Bibliographic Details
Main Authors: Jeremy L Peirce, Karl W Broman, Lu Lu, Elissa J Chesler, Guomin Zhou, David C Airey, Amanda E Birmingham, Robert W Williams
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-04-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2295257?pdf=render