Viridicatol Isolated from Deep-Sea <i>Penicillium</i> <i>Griseofulvum</i> Alleviates Anaphylaxis and Repairs the Intestinal Barrier in Mice by Suppressing Mast Cell Activation

Viridicatol Isolated from Deep-Sea <i>Penicillium</i> <i>Griseofulvum</i> Alleviates Anaphylaxis and Repairs the Intestinal Barrier in Mice by Suppressing Mast Cell Activation

Viridicatol is a quinoline alkaloid isolated from the deep-sea-derived fungus <i>Penicillium griseofulvum.</i> The structure of viridicatol was unambiguously established by X-ray diffraction analysis. In this study, a mouse model of ovalbumin-induced food allergy and the rat basophil leu...

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Bibliographic Details
Main Authors: Zhendan Shu, Qingmei Liu, Cuiping Xing, Yafen Zhang, Yu Zhou, Jun Zhang, Hong Liu, Minjie Cao, Xianwen Yang, Guangming Liu
Format: Article
Language:English
Published: MDPI AG 2020-10-01
Series:Marine Drugs
Subjects:
food allergy
deep-sea-derived viridicatol
X-ray single crystal
intestinal barrier
mast cell
calcium influx
Online Access:https://www.mdpi.com/1660-3397/18/10/517

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https://www.mdpi.com/1660-3397/18/10/517

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