MicroRNA-206, IL-4, IL-13, and INF-γ levels in lung tissue and plasma are increased by the stimulation of particulate matter with a diameter of ≤2.5μm, and are associated with the poor prognosis of asthma induced pulmonary arterial hypertension patients

MicroRNA-206, IL-4, IL-13, and INF-γ levels in lung tissue and plasma are increased by the stimulation of particulate matter with a diameter of ≤2.5μm, and are associated with the poor prognosis of asthma induced pulmonary arterial hypertension patients

Background This study aimed to explore the prognostic value of particulate matter with a diameter of ≤2.5 μm (PM2.5)-related microRNA-206 combined with interleukin (IL)-4, IL-13 and interferon-γ (INF-γ) in asthma induced pulmonary arterial hypertension (PAH). Methods Fifty SPF BALB/c mice were divid...

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Bibliographic Details
Main Authors: Shaohua Li, Xiaoning Ma, Jianli Xie, Xixin Yan, Wuzhuang Sun
Format: Article
Language:English
Published: Taylor & Francis Group 2021-02-01
Series:Clinical and Experimental Hypertension
Subjects:
pulmonary arterial hypertension
asthma
pm2.5
prognosis
inflammatory
Online Access:http://dx.doi.org/10.1080/10641963.2020.1836192

Internet

http://dx.doi.org/10.1080/10641963.2020.1836192

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