Convenient and Controllable Synthesis of Poly(2-oxazoline)-Conjugated Doxorubicin for Regulating Anti-Tumor Selectivity

Polyethylene glycol (PEG)–doxorubicin (DOX) conjugation is an important strategy to improve toxicity and enhance clinically therapeutic efficacy. However, with the frequent use of PEG-modified drugs, the accumulation of anti-PEG antibodies has become a tough issue, which limits the application of PE...

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Bibliographic Details
Main Authors: Min Zhou, Ruxin Cui, Zhengjie Luo, Zihao Cong, Ning Shao, Ling Yuan, Jiawei Gu, Hongyan He, Runhui Liu
Format: Article
Language:English
Published: MDPI AG 2023-07-01
Series:Journal of Functional Biomaterials
Subjects:
Online Access:https://www.mdpi.com/2079-4983/14/7/382